Maybe they covered all the risks with him off screen or maybe they didnt discuss every detail with him, but Wade was shown to be extremely familiar with, and a member of, the. He willingly signs up for a super questionable experiment to cure his cancer. Deadpool is also mentioned in X2: X-Men United and X-Men: The Official Game. Deadpool (the first one) was a terrible person and the villain of the movie. This version of Deadpool was also portrayed by Reynolds and appears in Deadpool, Deadpool: No Good Deed, Deadpool 2 and the modified re-release of Deadpool 2 called Once Upon A Deadpool. The second is the character Brolin played in the mainstream Marvel Cinematic Universe.
The first is a reference to the movie The Goonies which featured a long-dead pirate named One-Eyed Willie. For example, during the events of Deadpool 2, Deadpool calls Cable "One-Eyed Willie" and "Thanos", referencing two characters that Cable's actor Josh Brolin was involved in. Subsequent appearances of Deadpool have been closer to the snarkier version seen in the comic books and possesses the same self-awareness of people and events that a character in a comic book or a film would not normally have.
This version was given retractable metal claws similar to Wolverine's and had his mouth sewn shut because he wouldn't stop talking prior to the enhancements. The first appearance of Deadpool in an X-Men film occurred in X-Men Origins: Wolverine. In Wilson's case, the mutant genes gave him an accelerated healing ability and increases to other abilities like stamina, strength and more. During the process, he learned the real purpose was to create super soldiers by injecting them with a serum that would activate dormant mutant genes.
Deadpool, born Wade Wilson, is a mercenary that received superpowers after undergoing what he thought was an experimental treatment for cancer.